What Causes Cystic Acne and How to Finally Find Relief
- Blog Admin

- 12 minutes ago
- 15 min read
Cystic acne isn't just a simple pimple. It’s a deep, painful inflammatory reaction that stems from a perfect storm of excess oil, clogged pores, and bacteria brewing far beneath the skin's surface. This is exactly why it feels so different from other breakouts and why it demands a completely different approach to get it under control.
Decoding the Formation of a Cyst
To really get what causes cystic acne, think of it as a chain reaction happening deep inside your skin. It has absolutely nothing to do with having dirty skin or bad hygiene; it’s an internal process that's gone into overdrive.
This whole process unfolds in three key stages, with each one building on the last to create those painful, under-the-skin cysts that are so notoriously tough to manage.
The Three Core Stages of a Cyst
First, your skin’s sebaceous glands start working overtime, producing way too much sebum. This is the oily stuff that’s meant to keep your skin lubricated. A little bit is great, but an oversupply creates the perfect breeding ground for acne. Understanding the root of this overproduction is a big first step, and learning about oily skin causes and prevention can give you a solid foundation.
Next, all that extra oil mixes with dead skin cells. This creates a thick, sticky plug that completely clogs the hair follicle, or pore. Now the oil and bacteria are trapped deep inside with no way out.
Finally, a common skin bacterium called C. acnes—which usually just hangs out on the skin without causing any trouble—gets trapped in that clogged follicle. In this oily, oxygen-free environment, the bacteria multiply like crazy. Your body’s immune system flags this as a major threat and launches a full-blown inflammatory attack to fight it.
This diagram shows you exactly how a simple clog can escalate into that deep, angry inflammation.

As you can see, it's that final stage—the intense inflammation—that separates a minor pimple from a deep, painful cyst.
To put it simply, here are the four key things that have to happen for a cyst to form.
The Four Core Factors of a Cystic Breakout
Core Factor | How It Contributes to Cystic Acne |
|---|---|
Excess Sebum | Creates an oily environment where acne-causing bacteria can thrive. |
Clogged Follicles | Dead skin cells and oil form a plug, trapping bacteria deep within the pore. |
Bacterial Overgrowth | Trapped C. acnes bacteria multiply rapidly in the clogged, oxygen-poor follicle. |
Inflammatory Response | The immune system attacks the bacteria, causing intense swelling, redness, and pain. |
This internal battle results in a large, swollen, and tender cyst. The inflammation is so severe that it can actually damage the healthy skin tissue around the follicle. This is why cystic acne carries a much higher risk of leaving behind permanent scars compared to other types of acne.
Because this whole process happens so far beneath the surface, most over-the-counter creams just can't reach the source of the problem. This is where professional guidance becomes crucial.
At Skinsation Aesthetics in London, Ontario, we focus on treatments that get to the root of these deep-seated causes. Our goal is to calm the inflammation and stop the cycle from repeating itself. Understanding how these cysts form is the first step toward finding a real, lasting solution.
The Unseen Influence of Hormones and Genetics
When a deep, painful cyst shows up out of nowhere, it’s so easy to feel like you did something wrong. But the truth is, the most powerful factors are often completely out of your control. Two of the biggest drivers behind cystic acne are hormones and genetics, both working silently under the skin to set the stage for a breakout.
Understanding these internal triggers is the first step toward finding a treatment that actually works with your body, not against it. It's about recognizing that this isn't a personal failure—it's a common biological journey.
The Hormonal Connection to Cystic Acne
Hormones are basically your body's chemical messengers, and a group called androgens plays a huge role in acne. You might hear them called "male hormones," but androgens like testosterone are present and necessary for everyone. On the skin, their main job is to tell your sebaceous glands to produce oil (sebum).
When your androgen levels are steady, everything works just fine. But when they start to fluctuate, they can send oil production into overdrive.
Puberty: This is the most famous trigger. A massive surge in androgens kicks sebum production into high gear, which is why acne often starts in the teen years.
Menstrual Cycles: A lot of women notice breakouts that pop up like clockwork about a week before their period. This is tied directly to the natural hormonal shifts happening throughout the month.
Stress: When you're constantly stressed, your body pumps out cortisol. This stress hormone can also trigger an increase in androgens, leading to unexpected and often severe flare-ups.
This hormonal link is why acne is so incredibly common. The Canadian Dermatology Association estimates that acne affects around 5.6 million Canadians—that's almost 20% of the population. While over 80% of acne sufferers are between 12 and 24, it’s becoming more and more common for adults to deal with it, too. In fact, 20-30% of adults aged 20-40 are still experiencing acne.
If you're curious about how your hormones might be affecting your skin, you can even explore options like hormone level testing at home to get a clearer picture.
Your Genetic Blueprint and Acne
Ever heard a parent say, "Oh, I had terrible acne too"? There’s a very real reason for that. Your genetics are one of the strongest predictors of whether you'll develop severe acne. If one or both of your parents struggled with it, your chances of going through the same thing are much higher.
Think of your DNA as the blueprint for your skin. It can predetermine things like the size of your oil glands, how fast your skin sheds dead cells, and even how strongly your body reacts to acne-causing bacteria with inflammation.
Your genes basically dictate how sensitive your oil glands are to those hormonal signals we just talked about. Two people could have the exact same level of androgens, but the person with a genetic predisposition will have a much more intense reaction, leading to way more oil and inflammation. This is why some people seem to get away with anything, while others break out from the smallest trigger.
Having a genetic link doesn't mean you're doomed to have bad skin forever. What it does mean is that your skin might need a more dedicated and professional approach to get clear and stay that way.
If you’re fighting persistent breakouts that just won’t respond to over-the-counter products, it's very likely that hormones and genetics are a key part of the puzzle. We dive deeper into this in our guide to acne and hormone imbalances. Recognizing this connection is the first real step toward finding targeted treatments that can bring your skin back into balance.
Understanding Your Skin's Bacterial Balance
Let’s get one of the biggest myths about acne out of the way right now: it is not caused by having ‘dirty’ skin. The real answer to what causes cystic acne is far more complex, often starting with a delicate imbalance in your skin’s natural ecosystem—its microbiome.

Think of your skin as a thriving city filled with trillions of tiny residents, including good bacteria, fungi, and viruses. Most of the time, everyone lives together in perfect harmony, working to protect you from outside threats. But when the environment changes, some of these residents can multiply and cause serious trouble.
The Role of C. acnes Bacteria
In the story of cystic acne, one particular bacterium loves the spotlight: Cutibacterium acnes (or C. acnes). This microbe is a completely normal part of almost everyone’s skin, usually living quietly deep inside your hair follicles and minding its own business.
The problem isn't the bacteria's presence; it's the environment it lives in. When a pore gets clogged with a sticky mix of excess oil (sebum) and dead skin cells, it creates the perfect breeding ground for C. acnes.
Suddenly, this new environment is:
A buffet: Sebum is the bacteria's favourite food.
Oxygen-free: The clogged pore creates a sealed-off, anaerobic space where C. acnes can really flourish.
Trapped inside this ideal home with an endless food supply, the bacteria start multiplying like crazy. This sudden population explosion is what triggers your body's internal alarm system.
Interestingly, research shows that certain strains of this bacterium are more likely to provoke a severe reaction. One specific type, known as phylotype IA, has been strongly linked to moderate-to-severe acne, showing just how specific bacterial activity can set off the immune system. You can dig deeper into the science in the full research on acne pathogenesis.
The Body's Intense Inflammatory Response
Your immune system is a powerful defender. When it detects this massive overgrowth of C. acnes trapped deep within a follicle, it sees it as a major threat and launches an all-out attack.
This isn’t a small skirmish; it’s a full-on battle. Your body sends a flood of white blood cells and inflammatory chemicals to the area to wipe out the bacteria.
This internal war is what creates the hallmarks of a cyst: intense swelling, deep-seated redness, tenderness, and pain. That large, angry lump you feel isn't just bacteria—it's the visible aftermath of your body's own defense system going into overdrive.
This deep-seated inflammation is exactly why most topical, over-the-counter products don't stand a chance against cystic acne. They simply can't penetrate deep enough to get to the root of the problem. Trying to fix a cyst with a surface-level spot treatment is like trying to put out a fire in the basement by spraying water on the roof.
To really manage cystic acne, treatments need to do more than just kill bacteria. They have to calm this fierce internal battle, reduce the inflammation, and bring balance back to the skin's environment. This is essential for healing the skin and preventing the cellular damage that leads to scarring. A key part of this is supporting your skin barrier, which is your first line of defense. You can learn more in our complete guide on how to heal a damaged skin barrier.
How Acne Varies Across Different Skin Tones
Acne is a universal skin condition, but it definitely doesn't show up the same way on everyone. For Canada's diverse population, understanding how cystic acne looks and behaves across different skin tones is a huge part of finding the right treatment. The journey to clear skin isn't a one-size-fits-all deal; it needs a personal touch that respects the unique qualities of your complexion.

The biggest difference isn't just how the acne looks, but what it leaves behind. While inflammation is the main culprit behind cystic acne for all of us, in skin with more melanin (pigment), this inflammation can trigger a much stronger healing response.
Post-Inflammatory Hyperpigmentation in Deeper Skin Tones
One of the most frustrating challenges for people with olive, brown, and black skin is post-inflammatory hyperpigmentation (PIH). This is just a clinical way of saying the dark spots or patches that stick around long after a cyst has finally healed.
Think of it like this: when your skin is injured by the intense swelling of a cyst, its pigment-producing cells (melanocytes) go into overdrive as part of the healing process. This leads to way too much melanin being produced, leaving a dark mark where the breakout used to be.
In deeper skin tones, the melanocytes are naturally more active. This means that any inflammation—whether from a cyst, a cut, or even a simple scratch—has a much higher chance of leaving behind stubborn, long-lasting hyperpigmentation.
This is why, for many people of colour, the dark marks can feel more persistent and upsetting than the active acne itself. Clearing the breakout is only half the battle; the other half is getting back to an even, uniform skin tone.
Susceptibility and Severity Across Ethnicities
Beyond PIH, research also shows that genetics and ethnic background can influence how likely you are to get cystic acne and how severe it might be. Some groups may just be more prone to developing the deep, painful lesions that define this condition.
Evidence suggests that individuals of Asian and African descent are more likely to develop severe forms of acne. In one major study, cystic lesions were found in 18% of African-American patients and 25.5% of Hispanic patients, compared to just 10.5% of Asian patients. These are significant differences in how acne shows up. You can learn more about these ethnic variations in acne in the research.
The Need for Specialized Professional Care
These differences highlight why it's so important to work with a skincare professional who truly understands how to treat all skin tones safely and effectively. An aggressive treatment that works wonders for lighter skin could accidentally cause serious hyperpigmentation on deeper skin.
A knowledgeable practitioner knows how to:
Pick the right treatments: They’ll choose therapies like specific chemical peels or laser technologies that are proven to target acne without risking unwanted pigment changes.
Manage inflammation first: The key is to calm the inflammation from the cyst as quickly as possible. This dramatically lowers the chances of PIH developing in the first place.
Create a long-term plan: A winning strategy has to address both the active acne and the leftover hyperpigmentation, which often requires a multi-step approach.
At Skinsation Aesthetics in London, Ontario, our team has extensive experience treating the diverse skin tones of our community. We believe a treatment plan has to do more than just clear breakouts—it must protect and enhance the long-term health and evenness of your unique skin.
Lifestyle Triggers You Can Actually Influence
While you can't exactly rewrite your genetic code or stop hormonal shifts in their tracks, you can absolutely get a handle on the external factors that fan the flames. Figuring out what causes cystic acne flare-ups in your day-to-day life is all about taking back some control. It’s not about blame; it’s about making smart choices that support your skin’s health from the inside out.
So many of these triggers circle back to one main culprit: inflammation. Certain foods, chronic stress, and even the wrong skincare products can all tell your body to ramp up its inflammatory response, making you way more likely to see those deep, painful cysts pop up.
The Diet and Acne Connection
For years, people argued back and forth about whether diet really affected acne. Now, we have a growing pile of evidence showing a real connection, especially with two usual suspects: high-glycemic foods and dairy. This isn't a universal rule, but for many people, what’s on your plate can show up on your face.
High-glycemic foods are the ones your body burns through super fast, causing a huge spike in your blood sugar. Think white bread, sugary drinks, pastries, and all those processed snacks.
The Spike: Your blood sugar shoots up, and your body releases a flood of a hormone called insulin to deal with it.
The Hormone Cascade: This big insulin surge can actually lead to an increase in androgen hormones.
The Result: And as we know, androgens are the hormones that scream at your oil glands to produce more sebum, creating the perfect oily playground for acne to thrive.
Dairy, especially skim milk, has also been connected to acne for some people. The thinking is that the hormones naturally present in milk can poke those same oil-producing glands and add to the inflammation problem.
This isn't about vowing off entire food groups for good. It's more about being a detective for your own skin. Try cutting back on high-sugar foods or dairy for a few weeks and just see what happens. A balanced diet packed with whole foods, veggies, and lean protein is a great way to help keep inflammation under control.
How Stress Wreaks Havoc on Your Skin
Ever notice a massive, angry cyst showing up right in the middle of a stressful week at work or during exam season? That’s not a coincidence. When you’re constantly stressed, your body is pumping out a hormone called cortisol.
Cortisol is basically your body's built-in alarm system. But when that alarm is always going off, it can throw everything out of whack. It can directly tell your oil glands to produce more sebum and also kicks off a body-wide inflammatory response. It’s a nasty one-two punch that creates the perfect storm for a cystic acne flare-up.
Finding healthy ways to manage stress isn't just good for your head—it's a non-negotiable part of any solid skincare plan.
Mindful Movement: Gentle activities like yoga or even a brisk walk around a local spot like London's Victoria Park can help bring those cortisol levels down.
Breathing Exercises: Seriously, just a few minutes of deep, focused breathing can calm your whole nervous system.
Prioritizing Sleep: Not getting enough sleep makes cortisol levels spike. Aiming for 7-8 hours a night can make a huge difference.
Skincare, Makeup, and Mechanical Triggers
What you put on your skin—and even what touches it—matters a whole lot. The wrong products or certain habits can sneakily clog your pores and cause inflammation, making the whole cycle of cystic acne even worse.
Comedogenic Products: Be on the lookout for makeup and skincare products that are labelled "non-comedogenic." This is just a fancy way of saying they’re designed not to clog your pores. Heavy, oily foundations or super thick creams can essentially trap oil and bacteria under a seal on your skin.
Acne Mechanica: This is a specific type of acne that’s triggered by friction, pressure, or something constantly rubbing on the skin. It became way more common during the pandemic with all the mask-wearing ("maskne"). Anything that repeatedly rubs against your skin—think a helmet strap, a tight collar, or even just holding your mobile phone against your cheek—can irritate the hair follicles and lead to deep, angry breakouts. Simply being aware of these pressure points can help you avoid a lot of unnecessary irritation and keep your skin much calmer.
Finding Your Path to Clearer Skin in London
Once you understand what's really going on with cystic acne—from the hormonal drivers to the deep-seated inflammation—it becomes crystal clear why this isn't a battle you can win with drugstore spot treatments. The problem is simple: the depth and severity of these cysts mean over-the-counter products just can't penetrate far enough to do any good. They're literally out of their league.
And whatever you do, resist the urge to pop or squeeze a cyst. It’s a one-way ticket to more pain, raging inflammation, and the kind of scarring that sticks around for good. Because the inflammation is so deep, all that pressure can easily rupture the follicle wall underneath the skin, spreading the infection and turning a bad situation into a much, much worse one.
Why Professional Guidance Is Essential
When it comes to cystic acne, getting professional help isn't just a good idea—it's the only way to get real, lasting relief. A qualified skin expert can properly diagnose your specific condition, pinpoint your main triggers, and build a personalized plan that gets to the root cause of the problem.
This is where the cycle of frustration finally ends and a real strategy begins. Instead of playing a guessing game with products, you get a clear roadmap designed for your skin’s unique needs. Think of all the time, money, and emotional energy you'll save.
Advanced Treatments for Deep Healing
Here at Skinsation Aesthetics in London, Ontario, we look past the surface-level symptoms to tackle the deep inflammation that defines cystic acne. Our entire approach is built on calming the skin down, managing bacteria, and promoting profound healing to stop future breakouts in their tracks and minimize scarring.
We offer specialized services that are designed to make a genuine difference:
Chemical Peels: We use medical-grade peels with powerful ingredients like salicylic acid that don't just exfoliate the surface, but also dive deep into the pores. This helps clear out blockages, get oil production under control, and soothe the intense inflammation that comes with cysts.
Microneedling: This treatment creates tiny, controlled micro-injuries in the skin, which kicks your body’s natural healing process into high gear. This response fires up collagen production—something that's absolutely critical for repairing skin texture and fading the acne scars left behind.
The real goal of professional treatment is to shut down the inflammatory cycle. By controlling the breakout at its source, we not only clear up what's there now but also dramatically lower the risk of post-inflammatory hyperpigmentation and permanent scars later on.
For anyone in London or Southwestern Ontario who is just tired of the painful breakouts and constant disappointment, the next step is clear. It’s time to stop fighting this alone and partner with professionals who actually understand the science of your skin. To see what can be done, learn more about our London, Ontario acne treatment clinic and how we can guide you.
Booking a professional consultation is the single most powerful step you can take towards getting your skin’s health back and reclaiming your confidence.
Your Cystic Acne Questions, Answered
Once you understand what's happening deep under your skin, it's normal to have a ton of questions about what to do next. Dealing with this kind of acne is a whole different ball game compared to a simple breakout. Here are some of the most common questions we get asked at the clinic.
Can I Treat Cystic Acne at Home?
While keeping up with a good, gentle home care routine is always important, cystic acne almost never clears up with at-home products alone. The real problem is that the inflammation is happening way down in the dermis, which is far too deep for most topical creams and serums to reach.
Whatever you do, don't try to pop or squeeze these deep cysts. It’s incredibly painful and a surefire way to make the inflammation worse, which can lead to permanent scarring. This is where professional help comes in. Treatments at a clinic like Skinsation Aesthetics are specifically designed to get to the root of the problem, targeting those deep lesions safely and effectively.
How Is Cystic Acne Different from Regular Pimples?
It really comes down to three things: depth, size, and pain. Your average pimples, like whiteheads or blackheads, are much smaller and closer to the surface. They tend to heal pretty quickly without much fuss.
Cystic acne is a completely different beast. It creates large, deep, painful, and often squishy nodules that are buried way beneath the skin. Because they're causing damage at a much deeper level, they carry a much higher risk of leaving behind permanent scars, like the pitted or "ice pick" type, long after the cyst itself is gone.
Does My Diet Really Cause My Cystic Acne?
This is a big one. While your diet isn't the single cause for everyone, it can absolutely be a major trigger for some people. There's a lot of solid research now that connects high-glycemic foods (think sugar, white bread, and other refined carbs) and even dairy with making acne worse for those who are already prone to it.
These kinds of foods can mess with hormones that crank up oil production and fuel inflammation all over your body. So, while cutting out sugar isn't a magic cure, shifting to a more balanced, low-glycemic diet can be a huge help in your overall plan to manage your acne. It’s all about calming things down from the inside out.
Ready to get off the rollercoaster and start a professional treatment plan that actually works? At Skinsation Aesthetics, our experts in London, Ontario, are ready to build a personalized strategy to help you finally get clear, healthy skin. Book your consultation with us today and take the first real step toward relief.


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